Product Description
Anti- NLRP2 Antibody | FNab05758 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Suppresses TNF-and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.
Immunogen: NLR family, pyrin domain containing 2
synonyms: NALP2, NBS1, PAN1, PYPAF2
Molecular weight (observed) : 105-110 kDa
Reactivity Species: Human, Mouse
Tested Application: ELISA, IHC, WB
Recomended Dillution : WB: 1:500-1:2000; IHC: 1:20-1:200
Research Area: Immunology