Product Description
Anti- OSBPL10 Antibody | FNab06017 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Probable lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane. Its ability to bind phosphatidylserine, suggests that it specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P (PubMed:23934110) (Probable) . Plays a role in negative regulation of lipid biosynthesis (PubMed:19554302) . Negatively regulates APOB secretion from hepatocytes (PubMed:19554302, PubMed:22906437) . Binds cholesterol and acidic phospholipids (PubMed:22906437) . Also binds 25-hydroxycholesterol (PubMed:17428193) . Binds phosphatidylserine (PubMed:23934110) .
Immunogen: oxysterol binding protein-like 10
synonyms: ORP10, OSBP9
Molecular weight (observed) : 75-80kd, 64kd
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IP
Recomended Dillution : WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Research Area: Metabolism