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Product Description
Anti- PAIP1 Antibody | FNab06116 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Acts as a coactivator in the regulation of translation initiation of poly (A) -containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
Immunogen: poly (A) binding protein interacting protein 1
synonyms: N/A
Molecular weight (observed) : 60 kDa, 51 kDa, 40 kDa
Reactivity Species: Human, Mouse, Rat, Monkey
Tested Application: ELISA, IHC, WB
Recomended Dillution : WB: 1:500-1:2000; IF: 1:20-1:200
Research Area: Metabolism
