Product Description
Anti- XRN2 Antibody | FNab09557 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Possesses 5'->3' exoribonuclease activity (By similarity) . May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Binds to RNA polymerase II (RNAp II) transcription termination R-loops formed by G-rich pause sites (PubMed:21700224) .
Immunogen: 5'-3' exoribonuclease 2
synonyms: XRN2, DHM1 like protein, DHP protein, 5' 3' exoribonuclease 2, 5 3 exoribonuclease 2
Molecular weight (observed) : 108 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IF
Recomended Dillution : WB: 1:200-1:1000
Research Area: Metabolism, Developmental biology