Product Description
Anti- MEK5 Antibody | FNab05117 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs) . The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.
Immunogen: mitogen-activated protein kinase kinase 5
synonyms: HsT17454, MAP kinase kinase 5, MAP2K5, MAPK/ERK kinase 5, MAPKK 5, MAPKK5, MEK 5, MEK5, MKK5, PRKMK5
Molecular weight (observed) : 50kd
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recomended Dillution : WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:100
Research Area: Cardiovascular, Metabolism, Signal Transduction