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Product Description
Anti- PTGES3 Antibody | FNab06918 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363) . Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes (PubMed:11274138, PubMed:12077419) . Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway (PubMed:24711448) .
Immunogen: prostaglandin E synthase 3 (cytosolic)
synonyms: P23, TEBP
Molecular weight (observed) : 21-23 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IF
Recomended Dillution : WB: 1:500-1:2000; IP: 1:200-1:2000; IF: 1:20-1:200
Research Area: Signal Transduction
![PTGES3 Antibody (Center) [AMR09607G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/865200/1157267/logo__92149.1659788186__40692.1659862368.png?c=2 "PTGES3 Antibody (Center) [AMR09607G]"){kind=logo}
