Product Description
Anti- RAB12 Antibody | FNab06995 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy (By similarity) .
Immunogen: RAB12, member RAS oncogene family
synonyms: RAB12, Ras related protein Rab 12
Molecular weight (observed) : 28 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IF, IP
Recomended Dillution : WB: 1:500-1:2000; IP: 1:500-1:1000 ; IHC: 1:20-1:200; IF: 1:50-1:500
Research Area: Signal Transduction