Product Description
Anti- VAPA Antibody | FNab09369 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Binds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites (PubMed:25447204) . The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface (PubMed:25447204) . With OSBPL3, may regulate ER morphology (PubMed:16143324) . May play a role in vesicle trafficking (PubMed:11511104, PubMed:19289470) .
Immunogen: VAMP (vesicle-associated membrane protein) -associated protein A, 33kDa
synonyms: 33 kDa VAMP associated protein, hVAP 33, VAMP A, VAMP associated protein A, VAP 33, VAP A, VAP33, VAPA
Molecular weight (observed) : 33 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB
Recomended Dillution : WB: 1:500-1:5000; IHC: 1:50-1:200;IF: 1:10-1:100; IP: 1:500-1:5000
Research Area: Signal Transduction