Product Description
Anti- VPS37A Antibody | FNab09440 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.
Immunogen: vacuolar protein sorting 37 homolog A (S. cerevisiae)
synonyms: ESCRT I complex subunit VPS37A, FLJ32642, FLJ42616, HCRP1, hVps37A, PQBP2, VPS37A
Molecular weight (observed) : 44 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IF, IP
Recomended Dillution : WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Research Area: Signal Transduction