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This antibody recognizes only the non-phosphorylated C-terminus of CXCR4 (residues 341-352). Phosphorylation of S346/347 blocks antibody binding. PMID: 24154522, 25451233.
We recommend dephosphorylation of samples using lambda phosphatase treatment. Please refer to application notes.
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
This product is a recombinant monoclonal antibody, which offers several advantages including: