Product Description
Phospho-NOMO1 (S1205) Antibody [APR05206G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This NOMO1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1205 of human NOMO1.
Cellular Localisation: Endoplasmic reticulum membrane; Single-pass membrane protein
Molecular Weight: 134324
Clone: Polyclonal
Gene Name: NOMO1
Gene ID: 23420
Function: Component of a ribosome-associated endoplasmic reticulum (ER) translocon complex involved in multi-pass membrane protein transport into the ER membrane and biogenesis (PubMed:32820719) . May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning, via its interaction with NCLN/Nicalin (By similarity) .
Summary: Tissue Location: Expressed in colon tumor tissue and in adjacent normal colonic mucosa.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: DB
Dilution: DB--1:500
Synonyms: Nodal modulator 1, pM5 protein, NOMO1, PM5