Product Description
OTUD6B Antibody (C-term) [APR05679G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This OTUD6B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-262 amino acids from the C-terminal region of human OTUD6B.
Cellular Localisation: N/A
Molecular Weight: 33813
Clone: Polyclonal
Gene Name: OTUD6B (HGNC:24281)
Gene ID: 51633
Function: [Isoform 1]: Deubiquitinating enzyme that may play a role in the ubiquitin-dependent regulation of protein synthesis, downstream of mTORC1 (PubMed:21267069, PubMed:27864334) . May associate with the protein synthesis initiation complex and modify its ubiquitination to repress translation (PubMed:27864334) . May also repress DNA synthesis and modify different cellular targets thereby regulating cell growth and proliferation (PubMed:27864334) . May also play a role in proteasome assembly and function (PubMed:28343629) .
Summary: N/A
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: FC, WB
Dilution: WB--1:1000 FC--1:10~50
Synonyms: OTU domain-containing protein 6B, DUBA-5, OTUD6B, DUBA5