Product Description
ACE Antibody (Ascites) [APG01476G] | Leading Biology
Product Category: Monoclonal Antibodies
Host: Mouse
Species Reactivity: M
Specificity: This ACE antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 1274-1306 amino acids from human ACE.
Cellular Localisation: [Angiotensin-converting enzyme, soluble form]: Secreted
Molecular Weight: 149715
Clone: Monoclonal
Gene Name: ACE
Gene ID: 1636
Function: Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety.
Summary: Tissue Location: Ubiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system and prostate. Isoform Testis-specific is expressed in spermatocytes and adult testis
Form: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:500~16000
Synonyms: Angiotensin-converting enzyme, ACE, 321-, Dipeptidyl carboxypeptidase I, Kininase II, CD143, Angiotensin-converting enzyme, soluble form, ACE, DCP, DCP1