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Product Description
ALB Antibody [APG01721G] | Leading Biology
Product Category: Monoclonal Antibodies
Host: Mouse
Species Reactivity: H
Specificity: This ALB antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 540-569 amino acids from human ALB.
Cellular Localisation: Secreted.
Molecular Weight: 69367
Clone: Monoclonal
Gene Name: ALB
Gene ID: 213
Function: Binds water, Ca (2+), Na (+), K (+), fatty acids, hormones, bilirubin and drugs (Probable) . Its main function is the regulation of the colloidal osmotic pressure of blood (Probable) . Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (PubMed:19021548) . Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity) . Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (By similarity) . The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood (By similarity) . The rank order of affinity is zinc > calcium > magnesium (By similarity) . Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli (PubMed:6234017) . Does not prevent iron uptake by the bacterial siderophore aerobactin (PubMed:6234017) .
Summary: Tissue Location: Plasma.
Form: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:500~1000
Synonyms: Serum albumin, ALB
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