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Product Description
CAPN6 Antibody [AMM02517G] | Leading Biology
Product Category: Monoclonal Antibodies
Host: Mouse
Species Reactivity: M
Specificity: This CAPN6 antibody is generated from a mouse immunized with a recombinant protein of human CAPN6.
Cellular Localisation: Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, spindle. Note=During mitose associated with the mitotic spindle. At telophase colocalized to the midbody spindle
Molecular Weight: 74576
Clone: Monoclonal
Gene Name: CAPN6
Gene ID: 827
Function: Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility. Does not seem to have protease activity as it has lost the active site residues (By similarity) .
Summary: Tissue Location: Expressed only in placenta.
Form: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:500~1:1000 WB--1:1000
Synonyms: Calpain-6, Calpain-like protease X-linked, Calpamodulin, CalpM, CAPN6, CALPM, CANPX
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