Product Description
MMP9 Antibody [AMM02382G] | Leading Biology
Product Category: Monoclonal Antibodies
Host: Mouse
Species Reactivity: H
Specificity: Purified His-tagged MMP9 protein (Fragment) was used to produced this monoclonal antibody.
Cellular Localisation: Secreted, extracellular space, extracellular matrix
Molecular Weight: 78458
Clone: Monoclonal
Gene Name: MMP9
Gene ID: 4318
Function: Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration (PubMed:2551898, PubMed:1480034, PubMed:12879005) . Could play a role in bone osteoclastic resorption (By similarity) . Cleaves KiSS1 at a Gly-|-Leu bond (PubMed:12879005) . Cleaves NINJ1 to generate the Secreted ninjurin-1 form (PubMed:32883094) . Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N- terminal one quarter fragments (PubMed:1480034) . Degrades fibronectin but not laminin or Pz-peptide.
Summary: Tissue Location: Detected in neutrophils (at protein level) (PubMed:7683678) . Produced by normal alveolar macrophages and granulocytes.
Form: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:500-1:2000
Synonyms: Matrix metalloproteinase-9, MMP-9, 92 kDa gelatinase, 92 kDa type IV collagenase, Gelatinase B, GELB, 67 kDa matrix metalloproteinase-9, 82 kDa matrix metalloproteinase-9, MMP9, CLG4B