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Product Description
MYBBP1A Antibody [AMM02562G] | Leading Biology
Product Category: Monoclonal Antibodies
Host: Mouse
Species Reactivity: H
Specificity: This MYBBP1A antibody is generated from a mouse immunized with a recombinant protein between 1104-1328 amino acids from human MYBBP1A.
Cellular Localisation: Cytoplasm. Nucleus. Nucleus, nucleolus. Note=Shuttles between the nucleus and cytoplasm. Nuclear import may be mediated by KPNA2, while export appears to depend partially on XPO1/CRM1 (By similarity) . Predominantly nucleolar. {ECO:0000250|UniProtKB:Q7TPV4}
Molecular Weight: 148855
Clone: Monoclonal
Gene Name: MYBBP1A
Gene ID: 10514
Function: May activate or repress transcription via interactions with sequence specific DNA-binding proteins (By similarity) . Repression may be mediated at least in part by histone deacetylase activity (HDAC activity) (By similarity) . Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2 (By similarity) . Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter (By similarity) . Has a role in rRNA biogenesis together with PWP1 (PubMed:29065309) .
Summary: N/A
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:5000
Synonyms: Myb-binding protein 1A, MYBBP1A, P160
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