Product Description
PLOD1 Antibody (C-term) [AMM22311G] | Leading Biology
Product Category: Monoclonal Antibodies
Host: Mouse
Species Reactivity: H
Specificity: This PLOD1 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 61-94 amino acids from the C-terminal region of human PLOD1.
Cellular Localisation: Rough endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side
Molecular Weight: 83550
Clone: Monoclonal
Gene Name: PLOD1
Gene ID: 5351
Function: Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils (By similarity) . Forms hydroxylysine residues in -Xaa-Lys- Gly- sequences in collagens (PubMed:8621606, PubMed:10686424, PubMed:15854030) . These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links (Probable) .
Summary: N/A
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:4000
Synonyms: Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1, 1.14.11.4, Lysyl hydroxylase 1, LH1, PLOD1, LLH, PLOD