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Product Description
SERPINB3 Antibody [APG02974G] | Leading Biology
Product Category: Monoclonal Antibodies
Host: Mouse
Species Reactivity: H
Specificity: This antibody is generated from a mouse immunized with a recombinant between 1-390 amino acids from human.
Cellular Localisation: Cytoplasm. Note=Seems to also be secreted in plasma by cancerous cells but at a low level
Molecular Weight: 44565
Clone: Monoclonal
Gene Name: SERPINB3
Gene ID: 6317
Function: May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH (2) -terminal kinase (JNK1) .
Summary: Tissue Location: Squamous cells. Expressed in some hepatocellular carcinoma (at protein level) .
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:4000
Synonyms: Serpin B3, Protein T4-A, Squamous cell carcinoma antigen 1, SCCA-1, SERPINB3, SCCA, SCCA1
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