Product Description
ALB Antibody (C-term) [APR07055G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, M
Specificity: This ALB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 540-569 amino acids from the C-terminal region of human ALB.
Cellular Localisation: Secreted.
Molecular Weight: 69367
Clone: Polyclonal
Gene Name: ALB
Gene ID: 213
Function: Binds water, Ca (2+), Na (+), K (+), fatty acids, hormones, bilirubin and drugs (Probable) . Its main function is the regulation of the colloidal osmotic pressure of blood (Probable) . Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (PubMed:19021548) . Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity) . Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (By similarity) . The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood (By similarity) . The rank order of affinity is zinc > calcium > magnesium (By similarity) . Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli (PubMed:6234017) . Does not prevent iron uptake by the bacterial siderophore aerobactin (PubMed:6234017) .
Summary: Tissue Location: Plasma.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: IHC-P-Leica, IF, FC, WB
Dilution: IHC-P-Leica--1:500 WB--1:1000
Synonyms: Serum albumin, ALB