Product Description
BRIP1 Antibody (N-term) [APR30656G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, M
Specificity: This BRIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-163 amino acids from the N-terminal region of human BRIP1.
Cellular Localisation: Nucleus. Cytoplasm
Molecular Weight: 140867
Clone: Polyclonal
Gene Name: BRIP1
Gene ID: 83990
Function: DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1.
Summary: Tissue Location: Ubiquitously expressed, with highest levels in testis.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Fanconi anemia group J protein, Protein FACJ, ATP-dependent RNA helicase BRIP1, BRCA1-associated C-terminal helicase 1, BRCA1-interacting protein C-terminal helicase 1, BRCA1-interacting protein 1, BRIP1, BACH1, FANCJ