Product Description
FAM125A Antibody (Center) [APR15933G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This FAM125A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 152-186 amino acids from the Central region of human FAM125A.
Cellular Localisation: Cytoplasm. Nucleus. Endosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Late endosome membrane; Peripheral membrane protein Note=Colocalizes with F-actin. Some fraction may be nuclear
Molecular Weight: 28783
Clone: Polyclonal
Gene Name: MVB12A
Gene ID: 93343
Function: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor.
Summary: Tissue Location: Ubiquitously expressed except in skeletal muscle.
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:2000
Synonyms: Multivesicular body subunit 12A, CIN85/CD2AP family-binding protein, ESCRT-I complex subunit MVB12A, Protein FAM125A, MVB12A, CFBP, FAM125A