Product Description
IL31 Antibody (N-term) [APR06163G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This IL31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-40 amino acids from the N-terminal region of human IL31.
Cellular Localisation: Secreted.
Molecular Weight: 18205
Clone: Polyclonal
Gene Name: IL31
Gene ID: 386653
Function: Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR (PubMed:15184896) . May function in skin immunity (PubMed:15184896) . Enhances myeloid progenitor cell survival in vitro (By similarity) . Induces RETNLA and serum amyloid A protein expression in macrophages (By similarity) .
Summary: Tissue Location: Detected at low levels in testis, bone marrow, skeletal muscle, kidney, colon, thymus, small intestine and trachea
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: IHC-P, FC, WB
Dilution: WB--1:1000 IHC-P--1:100~500 FC--1:10~50
Synonyms: Interleukin-31, IL-31, IL31