Product Description
(Mouse) Gnl3 Antibody (C-term) [AMM08711G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, M
Specificity: This Mouse Gnl3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 420-454 amino acids from the C-terminal region of Mouse Gnl3.
Cellular Localisation: Nucleus. Nucleus, nucleolus. Note=Shuttles between the nucleus and nucleolus. {ECO:0000250|UniProtKB:Q811S9}
Molecular Weight: 60786
Clone: Polyclonal
Gene Name: Gnl3
Gene ID: 30877
Function: May be required to maintain the proliferative capacity of stem cells (By similarity) . Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation.
Summary: Tissue Location: Expressed in the adult bone marrow population that is enriched in hematopoietic stem cells.
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:4000 WB--1:500 WB--1:1000
Synonyms: Guanine nucleotide-binding protein-like 3, Nucleolar GTP-binding protein 3, Nucleostemin, Gnl3, Ns