Product Description
MYO5B Antibody (N-Term) [APR17509G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This MYO5B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 7-30 amino acids from MYO5B.
Cellular Localisation: Cytoplasm {ECO:0000250|UniProtKB:P70569}.
Molecular Weight: 213672
Clone: Polyclonal
Gene Name: MYO5B
Gene ID: 4645
Function: May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis.
Summary: N/A
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:2000
Synonyms: Unconventional myosin-Vb, MYO5B, KIAA1119