Product Description
NR4A2 Antibody (Center) [APR08823G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This NR4A2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 380-412 amino acids from the Central region of human NR4A2.
Cellular Localisation: Cytoplasm. Nucleus. Note=Mostly nuclear; oxidative stress promotes cytoplasmic localization
Molecular Weight: 66591
Clone: Polyclonal
Gene Name: NR4A2
Gene ID: 4929
Function: Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons (By similarity) .
Summary: Tissue Location: Expressed in a number of cell lines of T-cell, B- cell and fibroblast origin. Strong expression in brain tissue
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Nuclear receptor subfamily 4 group A member 2, Immediate-early response protein NOT, Orphan nuclear receptor NURR1, Transcriptionally-inducible nuclear receptor, NR4A2, NOT, NURR1, TINUR