Product Description
RASSF2 Antibody (N-Term) [ApR04839G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, M
Specificity: This RASSF2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 64-98 amino acids from human RASSF2.
Cellular Localisation: Nucleus. Cytoplasm. Chromosome, centromere, kinetochore. Note=Translocates to the cytoplasm in the presence of STK3/MST2 AND STK4/MST1
Molecular Weight: 37790
Clone: Polyclonal
Gene Name: RASSF2
Gene ID: 9770
Function: Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.
Summary: Tissue Location: Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines.
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:2000
Synonyms: Ras association domain-containing protein 2, RASSF2, KIAA0168