Product Description
SLC2A1 Antibody (C-term) [APR10053G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This SLC2A1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 464-497 amino acids from the C-terminal region of human SLC2A1.
Cellular Localisation: Cell membrane; Multi-pass membrane protein. Melanosome. Photoreceptor inner segment {ECO:0000250|UniProtKB:P17809}. Note=Localizes primarily at the cell surface (PubMed:18245775, PubMed:19449892, PubMed:23219802, PubMed:25982116, PubMed:24847886) . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065)
Molecular Weight: 54084
Clone: Polyclonal
Gene Name: SLC2A1 (HGNC:11005)
Gene ID: 6513
Function: Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake (PubMed:18245775, PubMed:19449892, PubMed:25982116, PubMed:27078104, PubMed:10227690) . Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses (PubMed:18245775, PubMed:19449892) . Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain (PubMed:10227690) . In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors (By similarity) .
Summary: Tissue Location: Detected in erythrocytes (at protein level) . Expressed at variable levels in many human tissues
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Solute carrier family 2, facilitated glucose transporter member 1, Glucose transporter type 1, erythrocyte/brain, GLUT-1, HepG2 glucose transporter, SLC2A1, GLUT1