Product Description
RAB27B Antibody (Center) [AMM07461G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This RAB27B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-150 amino acids from the Central region of human RAB27B.
Cellular Localisation: Membrane; Lipid-anchor. Late endosome
Molecular Weight: 24608
Clone: Polyclonal
Gene Name: RAB27B
Gene ID: 5874
Function: Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion (PubMed:30771381) . Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1 (PubMed:21775604) . May be involved in targeting uroplakins to urothelial apical membranes (By similarity) .
Summary: Tissue Location: Expressed primarily in testis.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P
Dilution: WB--1:1000 IHC-P--1:100~500
Synonyms: Ras-related protein Rab-27B, C25KG, RAB27B