Product Description
SEPT11 Antibody (Center) [APR13263G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This SEPT11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 353-382 amino acids from the Central region of human SEPT11.
Cellular Localisation: Cytoplasm, cytoskeleton. Cell junction, synapse. Cell projection, dendritic spine. Cell projection, axon Note=Partly colocalizes with stress fibers and microtubules. During bacterial infection, displays a collar shape structure next to actin at the pole of invading bacteria
Molecular Weight: 49398
Clone: Polyclonal
Gene Name: SEPTIN11 (HGNC:25589)
Gene ID: 55752
Function: Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential) . May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity (By similarity) . During Listeria monocytogenes infection, not required for the bacterial entry process, but restricts its efficacy.
Summary: Tissue Location: Widely expressed, except in leukocytes.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Septin-11, SEPT11