Euro
USD
British Pound
NULL
![SPOPL Antibody (Center) [APR03736G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/864542/1156609/logo__92149.1659788186__64270.1659860214.png?c=2 "SPOPL Antibody (Center) [APR03736G]"){kind=logo}
![SPOPL Antibody (Center) [APR03736G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/864542/1156609/logo__92149.1659788186__64270.1659860214.png?c=2 "SPOPL Antibody (Center) [APR03736G]"){kind=logo}
Product Description
SPOPL Antibody (Center) [APR03736G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This SPOPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-249 amino acids from the Central region of human SPOPL.
Cellular Localisation: Nucleus.
Molecular Weight: 44647
Clone: Polyclonal
Gene Name: SPOPL
Gene ID: 339745
Function: Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, but with relatively low efficiency. Cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL are less efficient than ubiquitin ligase complexes containing only SPOP. May function to down-regulate the activity of cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin- protein ligase complexes that contain SPOP.
Summary: N/A
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P, FC
Dilution: WB--1:1000 IHC-P--1:100~500 FC--1:10~50
Synonyms: Speckle-type POZ protein-like, HIB homolog 2, Roadkill homolog 2, SPOPL
![SPOPL Antibody (Center) [APR03736G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/864542/1156609/logo__92149.1659788186__64270.1659860214.png?c=2 "SPOPL Antibody (Center) [APR03736G]"){kind=logo}
