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Product Description
DLL4 Antibody [APR33634G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: M, Rat
Specificity: This DLL4 antibody is generated from a rabbit immunized with a recombinant protein from the human region of human DLL4.
Cellular Localisation: Cell membrane; Single-pass type I membrane protein
Molecular Weight: 74605
Clone: Polyclonal
Gene Name: DLL4
Gene ID: 54567
Function: Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954) . Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (PubMed:20616313) . Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (By similarity) . During spinal cord neurogenesis, inhibits V2a interneuron fate (PubMed:17728344) .
Summary: Tissue Location: Expressed in vascular endothelium.
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:2000
Synonyms: Delta-like protein 4, Drosophila Delta homolog 4, Delta4, DLL4
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