Product Description
MAGI2 Antibody (C-term) [APR33074G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: M, Rat
Specificity: This MAGI2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1123-1156 amino acids from the C-terminal region of human MAGI2.
Cellular Localisation: Cytoplasm. Late endosome. Cell junction, synapse, synaptosome. Cell membrane; Peripheral membrane protein Note=Localized diffusely in the cytoplasm before nerve growth factor (NGF) stimulation. Recruited to late endosomes after NGF stimulation Membrane-associated in synaptosomes (By similarity) .
Molecular Weight: 158754
Clone: Polyclonal
Gene Name: MAGI2
Gene ID: 9863
Function: Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in nerve growth factor (NGF) -induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth.
Summary: Tissue Location: Specifically expressed in brain.
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:2000
Synonyms: Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, Atrophin-1-interacting protein 1, AIP-1, Atrophin-1-interacting protein A, Membrane-associated guanylate kinase inverted 2, MAGI-2, MAGI2, ACVRINP1, AIP1, KIAA0705