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Product Description
Phospho-MYPT1 (Thr696) Antibody [APR33507G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: M
Specificity: This Phospho-MYPT1 (Thr696) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 669-702 amino acids from human MYPT1.
Cellular Localisation: Cytoplasm. Cytoplasm, cytoskeleton, stress fiber. Note=Also along actomyosin filaments
Molecular Weight: 115281
Clone: Polyclonal
Gene Name: PPP1R12A (HGNC:7618)
Gene ID: 4659
Function: Key regulator of protein phosphatase 1C (PPP1C) . Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity.
Summary: Tissue Location: Expressed in striated muscles, specifically in type 2a fibers (at protein level) .
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:500
Synonyms: Protein phosphatase 1 regulatory subunit 12A, Myosin phosphatase-targeting subunit 1, Myosin phosphatase target subunit 1, Protein phosphatase myosin-binding subunit, PPP1R12A, MBS, MYPT1
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