Product Description
PIP4K2C Antibody (N-term) [AMM07196G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: M, Rat
Specificity: This PIP4K2C antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 23-57amino acids from the N-terminal region of human PIP4K2C.
Cellular Localisation: Endoplasmic reticulum {ECO:0000250|UniProtKB:O88370}. Cytoplasm {ECO:0000250|UniProtKB:O88370}
Molecular Weight: 47300
Clone: Polyclonal
Gene Name: PIP4K2C (HGNC:23786)
Gene ID: 79837
Function: Phosphatidylinositol 5-phosphate 4-kinase with low enzymatic activity. May be a GTP sensor, has higher GTP-dependent kinase activity than ATP-dependent kinase activity. PIP4Ks negatively regulate insulin signaling through a catalytic-independent mechanism. They interact with PIP5Ks and suppress PIP5K-mediated PtdIns (4, 5) P2 synthesis and insulin- dependent conversion to PtdIns (3, 4, 5) P3 (PubMed:31091439) .
Summary: N/A
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma, Phosphatidylinositol 5-phosphate 4-kinase type II gamma, PI (5) P 4-kinase type II gamma, PIP4KII-gamma, PIP4K2C, PIP5K2C