Product Description
ZNF516 Antibody (Center) [APR31919G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: M
Specificity: This ZNF516 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 518-547 amino acids from the Central region of human ZNF516.
Cellular Localisation: Nucleus {ECO:0000250|UniProtKB:Q7TSH3}.
Molecular Weight: 124289
Clone: Polyclonal
Gene Name: ZNF516 (HGNC:28990)
Gene ID: 9658
Function: Transcriptional regulator that binds to the promoter and activates the transcription of genes promoting brown adipose tissue (BAT) differentiation. Among brown adipose tissue-specific genes, binds the proximal region of the promoter of the UCP1 gene to activate its transcription and thereby regulate thermogenesis (By similarity) . May also play a role in the cellular response to replication stress (PubMed:23446422) .
Summary: N/A
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:500
Synonyms: Zinc finger protein 516, ZNF516, KIAA0222