Product Description
BATF3 Antibody (Center) [APR33351G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This BATF3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 58-89 amino acids from the Central region of human BATF3.
Cellular Localisation: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:12087103}
Molecular Weight: 14468
Clone: Polyclonal
Gene Name: BATF3
Gene ID: 55509
Function: AP-1 family transcription factor that controls the differentiation of CD8 (+) thymic conventional dendritic cells in the immune system. Required for development of CD8-alpha (+) classical dendritic cells (cDCs) and related CD103 (+) dendritic cells that cross- present antigens to CD8 T-cells and produce interleukin-12 (IL12) in response to pathogens (By similarity) . Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes.
Summary: N/A
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:2000
Synonyms: Basic leucine zipper transcriptional factor ATF-like 3, B-ATF-3, 21 kDa small nuclear factor isolated from T-cells, Jun dimerization protein p21SNFT, BATF3, SNFT