Product Description
BRD3 Antibody (C-term) [APR32534G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, M
Specificity: This BRD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 672-702 amino acids from the C-terminal region of human BRD3.
Cellular Localisation: Nucleus {ECO:0000250|UniProtKB:Q8K2F0}. Note=Detected on chromatin. {ECO:0000250|UniProtKB:Q8K2F0}
Molecular Weight: 79542
Clone: Polyclonal
Gene Name: BRD3
Gene ID: 8019
Function: Chromatin reader that recognizes and binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling and interaction with transcription factors (PubMed:18406326, PubMed:27105114) . Regulates transcription by promoting the binding of the transcription factor GATA1 to its targets (By similarity) .
Summary: Tissue Location: Ubiquitous.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P
Dilution: WB--1:1000 IHC-P--1:100~500
Synonyms: Bromodomain-containing protein 3, RING3-like protein, BRD3, KIAA0043, RING3L