Product Description
FIL1L Antibody (N-term) [APR31627G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This FIL1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-224 amino acids from the N-terminal region of human FIL1L.
Cellular Localisation: Cytoplasm. Membrane. Nucleus
Molecular Weight: 130382
Clone: Polyclonal
Gene Name: FILIP1L
Gene ID: 11259
Function: Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor-associated vasculature.
Summary: Tissue Location: Expressed in endothelial cells, colon and colon cancers. In the colon, expressed in the vasculature and muscularis mucosa. In colon cancer, strongly expressed in tumor stroma and the vasculature (at protein level) . Expressed in ovarian epithelial cells Down-regulated in ovarian cancer.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Filamin A-interacting protein 1-like, 130 kDa GPBP-interacting protein, 90 kDa GPBP-interacting protein, Protein down-regulated in ovarian cancer 1, DOC-1, FILIP1L, COL4A3BPIP, DOC1, GIP90