Product Description
HEL308 Antibody (Center) [APR32130G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, M
Specificity: This HEL308 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-428 amino acids from the Central region of human HEL308.
Cellular Localisation: N/A
Molecular Weight: 124131
Clone: Polyclonal
Gene Name: HELQ
Gene ID: 113510
Function: Single-stranded DNA-dependent ATPase and 5' to 3' DNA helicase (PubMed:11751861) . Involved in the repair of DNA cross-links and double-strand break (DSB) resistance. Participates in FANCD2- mediated repair. Forms a complex with POLN polymerase that participates in homologous recombination (HR) repair and is essential for cellular protection against DNA cross-links (PubMed:19995904) .
Summary: N/A
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P, FC
Dilution: WB--1:1000 IHC-P--1:100~500 FC--1:10~50
Synonyms: Helicase POLQ-like, Mus308-like helicase, POLQ-like helicase, HELQ, HEL308