Product Description
KLF17 Antibody (C-term) [APR32165G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This KLF17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-271 amino acids of human KLF17.
Cellular Localisation: Nucleus.
Molecular Weight: 42577
Clone: Polyclonal
Gene Name: KLF17
Gene ID: 128209
Function: Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development (By similarity) .
Summary: N/A
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, FC
Dilution: WB--1:1000 FC--1:10~50
Synonyms: Krueppel-like factor 17, Zinc finger protein 393, KLF17, ZNF393