Product Description
MEAF6 Antibody (C-Term) [APR33425G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This MEAF6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 120-154 amino acids from human MEAF6.
Cellular Localisation: Nucleus, nucleolus. Chromosome, centromere, kinetochore
Molecular Weight: 21635
Clone: Polyclonal
Gene Name: MEAF6 (HGNC:25674)
Gene ID: 64769
Function: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A (PubMed:14966270) . This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription (PubMed:14966270) . Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4 (PubMed:16387653, PubMed:24065767) . Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity (PubMed:18794358) .
Summary: N/A
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:2000
Synonyms: Chromatin modification-related protein MEAF6, MYST/Esa1-associated factor 6, Esa1-associated factor 6 homolog, Protein EAF6 homolog, hEAF6, Sarcoma antigen NY-SAR-91, MEAF6, C1orf149, EAF6