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Product Description
MGEA5 Antibody (N-Term) [APR33627G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This MGEA5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 236-269 amino acids from the human region of human MGEA5.
Cellular Localisation: [Isoform 3]: Nucleus
Molecular Weight: 102915
Clone: Polyclonal
Gene Name: OGA (HGNC:7056)
Gene ID: 10724
Function: [Isoform 1]: Cleaves GlcNAc but not GalNAc from O- glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4- methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl-beta- GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro) (PubMed:11148210) . Does not bind acetyl-CoA and does not have histone acetyltransferase activity (PubMed:24088714) .
Summary: Tissue Location: Ubiquitous. Shows highest expression in the brain, placenta and pancreas.
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB, FC, IHC-P
Dilution: IHC-P--1:100~500 FC--1:25 WB--1:2000
Synonyms: Protein O-GlcNAcase, OGA, 3.2.1.169, Beta-N-acetylglucosaminidase, 3.2.1.-, Beta-N-acetylhexosaminidase, Beta-hexosaminidase, Meningioma-expressed antigen 5, N-acetyl-beta-D-glucosaminidase, N-acetyl-beta-glucosaminidase, Nuclear cytoplasmic O-GlcNAcase and acetyltransferase, NCOAT, MGEA5, HEXC, KIAA0679, MEA5
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