Product Description
NKX6-2 Antibody (N-term) [APR31652G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This NKX6-2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-43 amino acids from the N-terminal region of human NKX6-2.
Cellular Localisation: Nucleus {ECO:0000250|UniProtKB:D3Z4R4}.
Molecular Weight: 29263
Clone: Polyclonal
Gene Name: NKX6-2
Gene ID: 84504
Function: Transcription factor with repressor activity involved in the regulation of axon-glial interactions at myelin paranodes in oligodendrocytes. Binds to the consensus DNA sequence 5'- (A/T) TTAATGA- 3'. In oligodendrocytes, binds to MBP and PLP1 promoter regions.
Summary: Tissue Location: Highest expression in brain.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Homeobox protein Nkx-62, Homeobox protein NK-6 homolog B, NKX6-2, GTX, NKX6B