Product Description
PAIP2 Antibody (N-term) [APR31450G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This PAIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-34 amino acids from the N-terminal region of human PAIP2.
Cellular Localisation: Cytoplasm.
Molecular Weight: 14984
Clone: Polyclonal
Gene Name: PAIP2
Gene ID: 51247
Function: Acts as a repressor in the regulation of translation initiation of poly (A) -containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly (A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly (A) RNP structure organization.
Summary: Tissue Location: Expressed at highest level in testis, but also abundant in brain, cervix, lung, ovary, placenta, adipose tissue, thymus and thyroid.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Polyadenylate-binding protein-interacting protein 2, PABP-interacting protein 2, PAIP-2, Poly (A) -binding protein-interacting protein 2, PAIP2, PAIP2A