Product Description
PRPF6 Antibody (C-term) [APR31361G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This PRPF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 807-836 amino acids from the C-terminal region of human PRPF6.
Cellular Localisation: Nucleus, nucleoplasm. Nucleus speckle. Note=Localized in splicing speckles
Molecular Weight: 106925
Clone: Polyclonal
Gene Name: PRPF6
Gene ID: 24148
Function: Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome (PubMed:28781166, PubMed:21549338) . Enhances dihydrotestosterone- induced transactivation activity of AR, as well as dexamethasone- induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation.
Summary: Tissue Location: Widely expressed..
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Pre-mRNA-processing factor 6, Androgen receptor N-terminal domain-transactivating protein 1, ANT-1, PRP6 homolog, U5 snRNP-associated 102 kDa protein, U5-102 kDa protein, PRPF6, C20orf14