Product Description
RNF217 Antibody (N-term) [APR31644G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This RNF217 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-40 amino acids from the N-terminal region of human RNF217.
Cellular Localisation: Membrane; Single-pass membrane protein. Cytoplasm
Molecular Weight: 59372
Clone: Polyclonal
Gene Name: RNF217
Gene ID: 154214
Function: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates the degradation of the iron exporter ferroportin/SLC40A1 and thus regulates iron homeostasis.
Summary: Tissue Location: Mainly expressed in testis and skeletal muscle.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Probable E3 ubiquitin-protein ligase RNF217, 632-, IBR domain-containing protein 1, RING finger protein 217, RNF217, C6orf172, IBRDC1