Product Description
SARS virus PUP1Antibody (C-term) [APR32223G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: S
Specificity: This SARS virus PUP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 245~274 amino acids from amino acid 250-280 of SARS virus PUP1.
Cellular Localisation: Virion. Host Golgi apparatus membrane; Multi-pass membrane protein. Host cell membrane; Multi-pass membrane protein Secreted. Host cytoplasm. Note=The cell surface expressed protein can undergo endocytosis. The protein is secreted in association with membranous structures
Molecular Weight: 30903
Clone: Polyclonal
Gene Name: 3a
Gene ID: 1489669
Function: Forms homotetrameric potassium sensitive ion channels (viroporin) and may modulate virus release. Up-regulates expression of fibrinogen subunits FGA, FGB and FGG in host lung epithelial cells. Induces apoptosis in cell culture. Downregulates the type 1 interferon receptor by inducing serine phosphorylation within the IFN alpha- receptor subunit 1 (IFNAR1) degradation motif and increasing IFNAR1 ubiquitination.
Summary: N/A
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: N/A
Dilution: N/A
Synonyms: Protein 3a, Accessory protein 3a, Protein U274, Protein X1, 3a