Product Description
ZDHHC20 Antibody (N-term) [APR31105G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This ZDHHC20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-54 amino acids from the N-terminal region of human ZDHHC20.
Cellular Localisation: Golgi apparatus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasm, perinuclear region
Molecular Weight: 42278
Clone: Polyclonal
Gene Name: ZDHHC20 (HGNC:20749)
Gene ID: 253832
Function: Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates (PubMed:27153536, PubMed:29326245, PubMed:33219126) . Catalyzes palmitoylation of Cys residues in the cytoplasmic C-terminus of EGFR, and modulates the duration of EGFR signaling by modulating palmitoylation-dependent EGFR internalization and degradation (PubMed:27153536) . Has a preference for acyl-CoA with C16 fatty acid chains (PubMed:29326245) . Can also utilize acyl-CoA with C14 and C18 fatty acid chains (PubMed:29326245) .
Summary: N/A
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P
Dilution: WB--1:1000 IHC-P--1:100~500
Synonyms: Probable palmitoyltransferase ZDHHC20, Zinc finger DHHC domain-containing protein 20, DHHC-20, ZDHHC20