Product Description
ANO7 Antibody (N-term) [APG01885G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This ANO7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-135 amino acids from the N-terminal region of human ANO7.
Cellular Localisation: [Isoform 1]: Cell membrane; Multi-pass membrane protein. Cell junction. Endoplasmic reticulum. Note=Concentrates at sites of cell-cell contact (PubMed:17308099) . Shows an intracellular localization according to PubMed:22075693 and PubMed:20056604
Molecular Weight: 105532
Clone: Polyclonal
Gene Name: ANO7
Gene ID: 50636
Function: Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity) . Does not exhibit calcium-activated chloride channel (CaCC) activity (PubMed:22075693) . May play a role in cell-cell interactions (PubMed:17308099) .
Summary: Tissue Location: Specifically expressed in epithelial cells of the prostate (at protein level) .
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, FC
Dilution: WB--1:2000 WB--1:1000 FC--1:10~50
Synonyms: Anoctamin-7, Dresden transmembrane protein of the prostate, D-TMPP, IPCA-5, New gene expressed in prostate, Prostate cancer-associated protein 5, Transmembrane protein 16G, ANO7, NGEP, PCANAP5, TMEM16G